This study confirmed that cardiovascular diseases are one of the leading causes of death worldwide, and chronic stress (a long-term stress condition where the body doesn’t have time to recover) is a significant factor in their development. However, until now, its role in the development of these diseases has been almost ignored, according to the press service of Tula University in Russia. This oversight is due to the fact that the scale used to diagnose cardiovascular disease risk only considers gender, age, blood pressure, cholesterol levels, and smoking status.
The proposed approach relies on an index defined by scientists called the ‘Stress-Related Cardiovascular Disease Risk,’ obtained by calculating the mathematical relationship between the occurrence of heart attacks and strokes and the Stress Resistance Index, previously patented at Tula University.
Scientists then analyzed data on fatal and non-fatal cardiovascular events (heart attacks and strokes) in these patients for the period from 2014 to 2025. It was found that as the Stress Resistance Index decreased, the frequency of cardiovascular events increased, and life expectancy decreased.
This enabled the development of a formula for a new index of stress-induced cardiovascular disease risk.





