Even after successful treatment, heart attack patients may suffer from serious complications, such as cardiac fibrosis (the appearance of rough scar tissue in the heart) or heart failure, a condition where the heart is unable to pump blood, according to a study published in the “RMG” medical journal.
To predict these outcomes, doctors use international risk measures like “GRACE 2.0,” “TIMI,” and “CADILLAC.” These measures consider clinical and laboratory data, including age, heart rate, and blood pressure.
One issue is that these measures do not consider molecular indicators, which might indicate a higher risk of complications. University specialists proposed a composite approach based on a comprehensive assessment: using the GRACE 2.0 scale with analysis of biological markers (substances whose concentration increases in the body) for myocardial stress—a condition where the heart is under increased stress.
During myocardial infarction, their levels rise, allowing for the detection of substances secreted by the heart muscle under increased stress conditions in the patient’s blood serum.
Anton Vorobyov, an associate professor in the Department of Cardiology at Surgut State University, commented: “We monitored patients for four years, which allowed us to assess the long-term role of these serum markers and determine specific threshold values associated with negative outcomes.”
According to scientists, the approach they proposed not only predicts complications but also allows for personalized treatment, such as using telemedicine techniques to remotely monitor at-risk patients.
