The technology, named “CAPPSID,” which stands for “Coordinated Activity of Prokaryotes and Small Viruses for Safe Intracellular Delivery,” was detailed in the journal “Nature Biomedical Engineering,” according to Science Daily. These bacteria carry specially designed viruses, transporting them to the tumor and protecting them until they reach the cancerous cells. Upon arrival, the bacteria self-destruct to release the viral DNA, which begins to destroy the cancer cells from within.
This technique is characterized by its ability to bypass the immune system’s defenses, as the bacteria maintain the virus’s stability until the moment of release, enhancing its efficiency. It also includes an innovative safety mechanism that prevents the virus from replicating outside the tumor, as its activity relies on a protease enzyme produced by the tumor, ensuring the treatment remains confined to cancerous cells without harming healthy tissues.
This achievement represents a significant step towards developing more precise and safer cancer treatments, opening new horizons in the battle against this disease.
